A Combination Approach To Treating The Flu
- John Hayes Jr, MD
- 2 days ago
- 3 min read

A combination approach to treating the flu is crucial. As flu season picks up, it’s more important than ever to understand how to protect yourself and what options exist if you get sick.
Early intervention and several treatment options and supportive strategies can make a HUGE difference in both symptom severity and recovery time.
Xofluza and Similar Medications
If you test positive for the flu within the first 48 hours of symptoms, antiviral treatment may help greatly.
Xofluza (baloxavir marboxil) is a single-dose, FDA approved, antiviral that works differently from older drugs like Tamiflu. It stops the virus from replicating and may shorten the course of illness if taken early.
Who it's for: Most adults and adolescents over 12
How it works: Inhibits flu virus replication
Benefit: One dose, shorter duration of symptoms
Note: It’s not a substitute for prevention but it can help stop flu in its tracks if taken fast.
Azelastine: A Nasal Spray with Surprising Benefits
Azelastine, an antihistamine nasal spray, is typically used for allergies but some studies suggest it may offer anti-viral properties, especially against respiratory viruses.
May reduce nasal viral load and inflammation
Easy to use alongside other treatments
Emerging interest in its potential to help reduce upper respiratory symptoms
While not FDA-approved specifically for flu, it’s being explored as part of broader respiratory care, especially in integrative protocols.
Nasal Saline Spray: used regularly cleans and rinses nasal membranes without side effects.
“Our results show nasal sprays work well to reduce the duration and severity of respiratory infections, and the interference with normal activities, which is particularly important in light of the winter infection surge the UK regularly experiences.
“The important finding of a reduction in the use of antibiotics is also potentially very important in the fight against antibiotic resistance, one of the major public health threats of our time.
“Given these results, our advice, particularly for those at higher risk from infections or those who get recurrent infections, is at the first sign of cough, sore throat, cold or flu like symptoms, use a nasal spray to prevent it from developing fully, and to use the sprays preventatively after close exposure to people with infections.”
Immune Support: Vitamin C, D, and Zinc
Vitamin C, vitamin D, and zinc can support your immune system especially if taken consistently during cold and flu season and adjusted levels at the first sign of infection.
Vitamin C
Antioxidant that supports immune cells
May slightly reduce the duration of viral illness
Vitamin D
Modulates immune response
Low D levels are linked to higher risk of respiratory infections
Ask for lab testing your blood levels regularly
Zinc
Supports immune cell function and antiviral defense
May help shorten cold and flu symptoms if started early
Don’t Wait, Act Fast - THIS IS KEY!!!
If you develop symptoms like fever, fatigue, chills, or body aches get tested ASAP!!!
Keep some FluA/B Covid Test Kits at Home! (use within 48 hours)
Ask your doctor if Xofluza or another antiviral is right for you
Support your immune system with targeted nutrients
Hydrate, rest, and avoid spreading the virus to others
Take the Next Step Toward Resilience
Flu recovery is faster when you combine evidence-based treatments with supportive care. Whether you're looking to prepare, treat, or recover, don’t guess, get expert guidance.
Our team can help to review your immune status, discuss antiviral options, and personalize your seasonal wellness and sickness plans.
Key References: https://www.cdc.gov/flu/treatment/antiviral-drugs.html
https://www.cdc.gov/flu/treatment/index.html https://www.southampton.ac.uk/news/2024/07/overcounter-nasal-sprays-could-keep-colds-and-flu-at-bay-study-finds.page
